BDBM489606 US10961249, Entry 17::US11220505, Entry 8::US20240300954, Entry 17

SMILES CCC1(CC)CC(CCN2CC3CN(CC3C2)c2cccc(c2)C#N)OC1=O

InChI Key InChIKey=HGPBWRNDLPLYDB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 489606   

TargetSigma intracellular receptor 2(Human)
Temple University

US Patent
LigandPNGBDBM489606(US10961249, Entry 17 | US11220505, Entry 8 | US202...)
Affinity DataIC50: 7nMAssay Description:A stock concentration of 5 nM 3H-1,3-di-(2-tolyl)guanidine (3H-DTG) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 7(Human)
Temple University

US Patent
LigandPNGBDBM489606(US10961249, Entry 17 | US11220505, Entry 8 | US202...)
Affinity DataIC50: 1.00E+4nMAssay Description:A stock concentration of 5 nM [3H]-5-Hydroxytryptamine ([3H]-5HT) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Aliqu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

TargetSigma intracellular receptor 2(Human)
Temple University

US Patent
LigandPNGBDBM489606(US10961249, Entry 17 | US11220505, Entry 8 | US202...)
Affinity DataIC50: 7nMAssay Description:A stock concentration of 5 nM 3H-1,3-di-(2-tolyl)guanidine (3H-DTG) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent