BDBM489594 US10961249, Entry 5::US11220505, Entry 3::US20240300954, Entry 5

SMILES CC(C)c1ccccc1N1CC2CN(CCC3CC4(CCCCC4)C(=O)O3)CC2C1

InChI Key InChIKey=HDGPAUBLUJEGSY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 489594   

TargetSigma intracellular receptor 2(Human)
Temple University

US Patent
LigandPNGBDBM489594(US10961249, Entry 5 | US11220505, Entry 3 | US2024...)
Affinity DataIC50: 2.40nMAssay Description:A stock concentration of 5 nM 3H-1,3-di-(2-tolyl)guanidine (3H-DTG) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 7(Human)
Temple University

US Patent
LigandPNGBDBM489594(US10961249, Entry 5 | US11220505, Entry 3 | US2024...)
Affinity DataIC50: 268nMAssay Description:A stock concentration of 5 nM [3H]-5-Hydroxytryptamine ([3H]-5HT) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Aliqu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

TargetSigma intracellular receptor 2(Human)
Temple University

US Patent
LigandPNGBDBM489594(US10961249, Entry 5 | US11220505, Entry 3 | US2024...)
Affinity DataIC50: 2.40nMAssay Description:A stock concentration of 5 nM 3H-1,3-di-(2-tolyl)guanidine (3H-DTG) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2025
Entry Details
Go to US Patent