BDBM489378 Example 12-7::US10961242, Compound 86::US11548883, Compound 86

SMILES O=C(Cn1cc(c(CN2CCC(=CC2)c2ccccc2)n1)-c1cnc(NC2Cc3ccccc3C2)nc1)N1CCc2[nH]nnc2C1

InChI Key InChIKey=IPGYLJCEYFPJFO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 489378   

TargetAutotaxin(Human)
Legochem Biosciences

US Patent
LigandPNGBDBM489378(US10961242, Compound 86 | Example 12-7 | US1154888...)
Affinity DataIC50: 3nMAssay Description:Two-fold dilution of each test compound solution (10 μM, 100% dimethyl sulfoxide) is carried out on 96-well V bottom plate (Costar 3363). After ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
Go to US Patent

TargetAutotaxin(Human)
Legochem Biosciences

US Patent
LigandPNGBDBM489378(US10961242, Compound 86 | Example 12-7 | US1154888...)
Affinity DataIC50: 3nMAssay Description:Two-fold dilution of each test compound solution (10 μM, 100% dimethyl sulfoxide) is carried out on 96-well V bottom plate (Costar 3363). After ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent