BDBM489351 Example 10-8::US10961242, Compound 68::US11548883, Compound 68

SMILES CCN1CC(C1)Oc1nn(CC(=O)N2CCc3[nH]nnc3C2)cc1-c1cnc(NC2Cc3ccccc3C2)nc1

InChI Key InChIKey=AETVBWZVKDOWHH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 489351   

TargetAutotaxin(Human)
Legochem Biosciences

US Patent
LigandPNGBDBM489351(US10961242, Compound 68 | Example 10-8 | US1154888...)
Affinity DataIC50: 1.80nMAssay Description:Two-fold dilution of each test compound solution (10 μM, 100% dimethyl sulfoxide) is carried out on 96-well V bottom plate (Costar 3363). After ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
Go to US Patent

TargetAutotaxin(Human)
Legochem Biosciences

US Patent
LigandPNGBDBM489351(US10961242, Compound 68 | Example 10-8 | US1154888...)
Affinity DataIC50: 1.80nMAssay Description:Two-fold dilution of each test compound solution (10 μM, 100% dimethyl sulfoxide) is carried out on 96-well V bottom plate (Costar 3363). After ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent