BDBM489344 2-[3-(azetidin-3-yloxy)-4-{2-[(2,3-dihydro-1H-inden-2-yl)amino]pyrimidin-5-yl}-1H-pyrazol-1yl]-1-{1H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridin-5-yl}ethan-1-one::Example 10-2::US10961242, Compound 62::US11548883, Compound 62

SMILES O=C(Cn1cc(c(OC2CNC2)n1)-c1cnc(NC2Cc3ccccc3C2)nc1)N1CCc2[nH]nnc2C1

InChI Key InChIKey=VWVRASTUFJRTHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 489344   

TargetAutotaxin(Human)
Legochem Biosciences

US Patent
LigandPNGBDBM489344(US10961242, Compound 62 | Example 10-2 | 2-[3-(aze...)
Affinity DataIC50: 2.40nMAssay Description:Two-fold dilution of each test compound solution (10 μM, 100% dimethyl sulfoxide) is carried out on 96-well V bottom plate (Costar 3363). After ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2021
Entry Details
Go to US Patent

TargetAutotaxin(Human)
Legochem Biosciences

US Patent
LigandPNGBDBM489344(US10961242, Compound 62 | Example 10-2 | 2-[3-(aze...)
Affinity DataIC50: 2.40nMAssay Description:Two-fold dilution of each test compound solution (10 μM, 100% dimethyl sulfoxide) is carried out on 96-well V bottom plate (Costar 3363). After ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
Go to US Patent