BDBM489225 US10961233, Example 86

SMILES Nc1nc(co1)C(=O)Nc1cc(ccc1Cl)N1CCN(CC1)S(=O)(=O)C1CCNCC1

InChI Key InChIKey=PPYLSXILUWAQPN-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 489225   

TargetBifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase(Human)
Lifearc

US Patent

LigandBDBM489225(US10961233, Example 86)Copy SMILESCopy InChI

Affinity DataIC50: 17.5nMAssay Description:5 μl WT full length PAICS (final assay concentration, fac, 2.5 nM) in basic buffer, added to black, non-binding, 384-well plates (Corning #3575)...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/4/2021
Entry Details
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