BDBM488094 2-((4-(2-((4- (Piperazin-1- yl)phenyl)amino) pyrimidin-4-yl)-3-(pyridin- 3-yl)-1H-pyrazol-1- yl)methyl)benzonitrile::US10954216, Example 157

SMILES N#Cc1ccccc1Cn1cc(c(n1)-c1cccnc1)-c1ccnc(Nc2ccc(cc2)N2CCNCC2)n1

InChI Key InChIKey=PWMFITOJMFBKMN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488094   

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandPNGBDBM488094(2-((4-(2-((4- (Piperazin-1- yl)phenyl)amino) pyrim...)
Affinity DataIC50: 5.60nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
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Date in BDB:
9/28/2021
Entry Details
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