BDBM487170 6-amino-3-(2,4-dichloro-3-(2- hydroxyethyl)-1H-pyrrolo[2,3- b]pyridin-5-yl)-2-fluoro-N,N- dimethylbenzamide::US10952995, Compound 1-26

SMILES CN(C)C(=O)c1c(N)ccc(c1F)-c1cnc2[nH]c(Cl)c(CCO)c2c1Cl

InChI Key InChIKey=NKULPSMXCYDPIP-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487170   

LigandPNGBDBM487170(6-amino-3-(2,4-dichloro-3-(2- hydroxyethyl)-1H-pyr...)
Affinity DataKi:  12nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent