BDBM486267 5-[2-(cyclopropylmethoxy)-5- methylsulfonylpheny]-1,4- dimethylpyridin-2-one::US10941160, Example 477

SMILES Cc1cc(=O)n(C)cc1-c1cc(ccc1OCC1CC1)S(C)(=O)=O

InChI Key InChIKey=OCIJSTSRCQSDTB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 486267   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM486267(5-[2-(cyclopropylmethoxy)-5- methylsulfonylpheny]-...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
US Patent