BDBM486248 5-(2-ethoxy-5-ethylsulfonylphenyl)-1,4 dimethylpyridin-2-one::US10941160, Example 458

SMILES CCOc1ccc(cc1-c1cn(C)c(=O)cc1C)S(O)(O)CC

InChI Key InChIKey=RQFQTLWYDZOTGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 486248   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM486248(5-(2-ethoxy-5-ethylsulfonylphenyl)-1,4 dimethylpyr...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
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Date in BDB:
9/20/2021
Entry Details
US Patent