BDBM486240 5-[2-(cyclopropylmethoxy)-5- ethylsulfonylphenyl]-1,3- dimethylpyridin-2-one::US10941160, Example 450

SMILES CCS(O)(O)c1ccc(OCC2CC2)c(c1)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=WTZPDSBZENNXSP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 486240   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM486240(5-[2-(cyclopropylmethoxy)-5- ethylsulfonylphenyl]-...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
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Date in BDB:
9/20/2021
Entry Details
US Patent