BDBM486221 US10947210, Compound 12-7A

SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCCc3ccccc3C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1

InChI Key InChIKey=ZTRGKWSPVVRROQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 486221   

TargetGenome polyprotein(HCV)
Cocrystal Pharma

US Patent
LigandPNGBDBM486221(US10947210, Compound 12-7A)
Affinity DataIC50: 100nMAssay Description:The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton X-100, 0.5 uM polyA:U16 substrate, purifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent