BDBM485969 US10947210, Compound 02-10F

SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCc3ccc(cc3)C(=O)\C=C(/O)C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1

InChI Key InChIKey=CFZHPCTYBOIMJH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 485969   

TargetGenome polyprotein(HCV)
Cocrystal Pharma

US Patent
LigandPNGBDBM485969(US10947210, Compound 02-10F)
Affinity DataIC50: 1.00E+3nMAssay Description:The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton X-100, 0.5 uM polyA:U16 substrate, purifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetGenome polyprotein(HCV)
Cocrystal Pharma

US Patent
LigandPNGBDBM485969(US10947210, Compound 02-10F)
Affinity DataEC50: <100nMAssay Description:HCV replicon assay is based on the luciferase reporter cell line (Huh-luc/neo-ET). This reporter cell line is a human liver carcinoma cell line (Huh-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent