BDBM485941 US10946019, Example 45

SMILES Cc1cc2c(C)nc(nc2n1-c1ccc(cc1)C(O)=O)-c1ccccc1

InChI Key InChIKey=NVAGQBBBCZUYMK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 485941   

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandPNGBDBM485941(US10946019, Example 45)
Affinity DataEC50:  2.50E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent