BDBM485768 (R)-3-((2,4- dimethylquinolin-5- yl)oxy)-N-methyl-3- (thiophen-2-yl)propan-1- amine::US10941138, Example 66

SMILES CNCC[C@@H](Oc1cccc2nc(C)cc(C)c12)c1cccs1

InChI Key InChIKey=YEZBCCGAGUDCGG-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 485768   

TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM485768((R)-3-((2,4- dimethylquinolin-5- yl)oxy)-N-methyl-...)
Affinity DataKi: <100nMAssay Description:Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent