BDBM485734 N-methyl-3-(4- methylthiazol-2-yl)-3- (quinolin-5-yloxy)propan- 1-amine::US10941138, Example 32

SMILES CNCCC(Oc1cccc2ncccc12)c1nc(C)cs1

InChI Key InChIKey=LIKXKZCGSBEXLL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 485734   

TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM485734(N-methyl-3-(4- methylthiazol-2-yl)-3- (quinolin-5-...)
Affinity DataKi:  300nMAssay Description:Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent