BDBM48569 MLS000087323::N-(3-chlorophenyl)-5-isopropyl-isoxazole-3-carboxamide::N-(3-chlorophenyl)-5-isopropylisoxazole-3-carboxamide::N-(3-chlorophenyl)-5-propan-2-yl-1,2-oxazole-3-carboxamide::N-(3-chlorophenyl)-5-propan-2-yl-3-isoxazolecarboxamide::SMR000023546::cid_3240071

SMILES CC(C)c1cc(no1)C(=O)Nc1cccc(Cl)c1

InChI Key InChIKey=JFZSPOLGILAGQH-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 48569   

LigandPNGBDBM48569(N-(3-chlorophenyl)-5-propan-2-yl-1,2-oxazole-3-car...)
Affinity DataIC50: 6.40E+4nMAssay Description:Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetTranscription factor p65(Human)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM48569(N-(3-chlorophenyl)-5-propan-2-yl-1,2-oxazole-3-car...)
Affinity DataEC50:  2.42E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetSurvival motor neuron protein(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM48569(N-(3-chlorophenyl)-5-propan-2-yl-1,2-oxazole-3-car...)
Affinity DataEC50:  860nMAssay Description:Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2019
Entry Details Article
PubMed