BDBM48562 5-(3-bromophenyl)-7-phenyl-1,5,6,7-tetrahydro-[1,2,3,4]tetrazolo[1,5-a]pyrimidine::5-(3-bromophenyl)-7-phenyl-1,5,6,7-tetrahydrotetrazolo[1,5-a]pyrimidine::5-(3-bromophenyl)-7-phenyl-4,5,6,7-tetrahydrotetrazolo[1,5-a]pyrimidine::MLS000042986::SMR000019413::cid_5771303

SMILES Brc1cccc(c1)C1CC(c2ccccc2)n2nnnc2N1

InChI Key InChIKey=BIFUUINQYFIGMS-UHFFFAOYSA-N

Data  1 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 48562   

LigandPNGBDBM48562(5-(3-bromophenyl)-7-phenyl-1,5,6,7-tetrahydro-[1,2...)
Affinity DataIC50: 6.40E+4nMAssay Description:Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetCorticotropin-releasing factor-binding protein(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM48562(5-(3-bromophenyl)-7-phenyl-1,5,6,7-tetrahydro-[1,2...)
Affinity DataEC50: >5.30E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetEndothelial PAS domain-containing protein 1(Human)
University of Texas Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM48562(5-(3-bromophenyl)-7-phenyl-1,5,6,7-tetrahydro-[1,2...)
Affinity DataKd:  883nMAssay Description:Binding affinity to wild type His6-Gbeta1-fused HIF-2alpha PAS-B domain (240 to 350) (unknown origin) expressed in Escherichia coli by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2016
Entry Details Article
PubMed