BDBM485068 US10934303, Cmpd No. 22m::US10934303, Example 64::US11285226, Compound 22m

SMILES CC(C)N1CCC(CC1)c1ccc(cc1)C(=C(\CCCO)c1ccccc1)\c1cccc(O)c1

InChI Key InChIKey=ANMDBOUDORUSLO-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 485068   

TargetEstrogen-related receptor gamma(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485068(US10934303, Example 64 | US10934303, Cmpd No. 22m ...)
Affinity DataIC50: 78nMAssay Description:ERRγ: The arylethene derivative of the present invention was sequentially added to a 384 well plate from a concentration of 10 μM to a fina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
Go to US Patent

TargetSteroid hormone receptor ERR1(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485068(US10934303, Example 64 | US10934303, Cmpd No. 22m ...)
Affinity DataIC50: 1.00E+4nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
Go to US Patent

TargetSteroid hormone receptor ERR2(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485068(US10934303, Example 64 | US10934303, Cmpd No. 22m ...)
Affinity DataIC50: 7.82E+3nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
Go to US Patent

TargetEstrogen receptor(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485068(US10934303, Example 64 | US10934303, Cmpd No. 22m ...)
Affinity DataIC50: 1.00E+4nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
Go to US Patent

TargetEstrogen-related receptor gamma(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485068(US10934303, Example 64 | US10934303, Cmpd No. 22m ...)
Affinity DataIC50: 415nMAssay Description:Binding affinity to ERRgamma (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR1(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485068(US10934303, Example 64 | US10934303, Cmpd No. 22m ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to ERRalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSteroid hormone receptor ERR2(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485068(US10934303, Example 64 | US10934303, Cmpd No. 22m ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to ERRbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485068(US10934303, Example 64 | US10934303, Cmpd No. 22m ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetEstrogen-related receptor gamma(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485068(US10934303, Example 64 | US10934303, Cmpd No. 22m ...)
Affinity DataIC50: 78nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
Go to US Patent

TargetSteroid hormone receptor ERR1(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485068(US10934303, Example 64 | US10934303, Cmpd No. 22m ...)
Affinity DataIC50: 1.00E+4nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
Go to US Patent

TargetSteroid hormone receptor ERR2(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485068(US10934303, Example 64 | US10934303, Cmpd No. 22m ...)
Affinity DataIC50: 7.82E+3nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
Go to US Patent

TargetEstrogen receptor(Human)
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485068(US10934303, Example 64 | US10934303, Cmpd No. 22m ...)
Affinity DataIC50: 1.00E+4nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2022
Entry Details
Go to US Patent