BDBM484181 2-(2-(12-isobutyl-4-oxa-8,12- diazadispiro[2.1.5.3]tridecan- 8-yl)ethyl)nicotinonitrile::US10927128, Example 102::US11649248, Example 102

SMILES CC(C)CN1CC2(CC2)OC2(CCN(CCc3ncccc3C#N)CC2)C1

InChI Key InChIKey=LUTNMZGPCMLKKZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 484181   

TargetAP-4 complex subunit sigma-1(Human)
Esteve Pharmaceuticals.

US Patent
LigandPNGBDBM484181(2-(2-(12-isobutyl-4-oxa-8,12- diazadispiro[2.1.5.3...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
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TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484181(2-(2-(12-isobutyl-4-oxa-8,12- diazadispiro[2.1.5.3...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent