BDBM484094 4-ethyl-9-isopentyl-2,2-dimethyl-1-oxa- 4,9-diazaspiro[5.5]undecan-3-one::US10927128, Example 15::US11649248, Example 15

SMILES CCN1CC2(CCN(CCC(C)C)CC2)OC(C)(C)C1=O

InChI Key InChIKey=RADKIQMWUOVFNE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 484094   

TargetAP-4 complex subunit sigma-1(Human)
Esteve Pharmaceuticals.

US Patent
LigandPNGBDBM484094(4-ethyl-9-isopentyl-2,2-dimethyl-1-oxa- 4,9-diazas...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484094(4-ethyl-9-isopentyl-2,2-dimethyl-1-oxa- 4,9-diazas...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent