BDBM484071 (S)-1-((R)-8-(1H- pyrrolo[3,2-b]pyridin-6- ylsulfonyl)-1-oxa-8- azaspiro[4.5]decan-3- ylamino)-3-(3- (cyclopropylsulfonyl) phenoxy)propan-2-ol::US10927123, Compound 309

SMILES O[C@@H](CN[C@H]1COC2(C1)CCN(CC2)S(=O)(=O)c1ccc2cc[nH]c2c1)COc1cccc(c1)S(=O)(=O)C1CC1

InChI Key InChIKey=GKKCQCNJVYYIFP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484071   

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM484071((S)-1-((R)-8-(1H- pyrrolo[3,2-b]pyridin-6- ylsulfo...)
Affinity DataIC50: 7.00E+3nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent