BDBM484054 (S)-1-((S)-8-(4'-(2- aminoethyl)biphenyl-3- ylsulfonyl)-l-oxa-8- azaspiro[4.5]decan-3- ylamino)-3-(3-(1- (hydroxymelhyl) cyclopropylsulfonyl) phenoxy)propan-2-ol::US10927123, Compound 211

SMILES NCCc1ccc(cc1)-c1cccc(c1)S(=O)(=O)N1CCC2(C[C@@H](CO2)NC[C@H](O)COc2cccc(c2)S(=O)(=O)C2(CO)CC2)CC1

InChI Key InChIKey=MBIXCUIOHLJBGG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484054   

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandPNGBDBM484054((S)-1-((S)-8-(4'-(2- aminoethyl)biphenyl-3- ylsulf...)
Affinity DataIC50: 2.62E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
Go to US Patent