BDBM483882 (S)-1-(4-(3-(4- chlorophenoxy)- benzyl)-2- methylpiperazine-1- carbonyl)-4-methyl- 1H-pyrazole-3- carboxylic acid::US10927105, Ex 442::US11655217, Example 442

SMILES C[C@H]1CN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CCN1C(=O)n1cc(C)c(n1)C(O)=O

InChI Key InChIKey=LVKSMZTYIVEREB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483882   

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM483882(US10927105, Ex 442 | (S)-1-(4-(3-(4- chlorophenoxy...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM483882(US10927105, Ex 442 | (S)-1-(4-(3-(4- chlorophenoxy...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent