BDBM483857 4-chloro-1-(4-(3- ((4-(trifluoromethyl)- pyridin-2- yl)oxy)benzyl) piperazine-1- carbonyl)- 1H-pyrazole-3- carboxylic acid::US10927105, Ex 399::US11655217, Example 399

SMILES OC(=O)c1nn(cc1Cl)C(=O)N1CCN(Cc2cccc(Oc3cc(ccn3)C(F)(F)F)c2)CC1

InChI Key InChIKey=KIJUHRZRKCVZMK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483857   

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483857(US10927105, Ex 399 | 4-chloro-1-(4-(3- ((4-(triflu...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483857(US10927105, Ex 399 | 4-chloro-1-(4-(3- ((4-(triflu...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent