BDBM483619 N-[(7S)-4-fluorobicyclo[4.2.0]octa-1,3,5- trien-7-yl]-N''-hydroxy-4-{[6-(S- methylsulfonimidoyl)spiro[3.3]heptan-2- yl]amino}-1,2,5-oxadiazole-3- carboximidamide (isomer 1)::US10927086, Example 74::US10927086, Example 75
SMILES CS(=N)(=O)C1CC2(CC(C2)Nc2nonc2\C(N[C@@H]2Cc3ccc(F)cc23)=N/O)C1
InChI Key InChIKey=FLEFTWIWJCXOLE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 483619
Affinity DataIC50: 73.7nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
Affinity DataIC50: 90.4nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
