BDBM483611 4-({2-[(N,S- dimethylsulfonimidoyl)amino]ethyl}amino)- N-[(7S)-4-fluorobicyclo[4.2.0]octa- 1,3,5-trien-7-yl]-N''-hydroxy-1,2,5- oxadiazole-3-carboximidamide (isomer 1)::US10927086, Example 66::US10927086, Example 67

SMILES CN=S(C)(=O)NCCNc1nonc1\C(N[C@H]1Cc2ccc(F)cc12)=N/O

InChI Key InChIKey=LIXKJVYHRPDCCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483611   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483611(US10927086, Example 67 | 4-({2-[(N,S- dimethylsulf...)
Affinity DataIC50: 63.7nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM483611(US10927086, Example 67 | 4-({2-[(N,S- dimethylsulf...)
Affinity DataIC50: 80.8nMAssay Description:HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent