BDBM483413 US10919911, Example 35

SMILES C[C@H]1Cn2cnnc2-c2cccc(NC(=O)c3cc(c(C)cc3F)-n3cnc(c3)C3CC3)c2O1

InChI Key InChIKey=PUGBLHGLBHMIRO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 483413   

LigandPNGBDBM483413(US10919911, Example 35)
Affinity DataIC50: 2.5nMAssay Description:Base Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, and 1% DMSO were used for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent