BDBM483325 US10919895, Compound Ia-09

SMILES CCCCNCc1cnc(Cn2c(O)nc3c(N)nc(OCCCC)nc23)cn1

InChI Key InChIKey=XSUXNQGJDIWOFY-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483325   

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM483325(US10919895, Compound Ia-09)
Affinity DataEC50:  89nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent

TargetInterleukin-6(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM483325(US10919895, Compound Ia-09)
Affinity DataEC50:  420nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Technologies clear, V-bottom 384-well plate using ECHO acoustic liquid han...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent