BDBM483000 US10919885, Compound No. 148

SMILES O=C(Nc1cnn(Cc2ccccc2)c1)c1cc(on1)-c1ccncn1

InChI Key InChIKey=IEQKUTWVYAHKLS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483000   

TargetStearoyl-CoA desaturase(Human)
Yumanity Therapeutics

US Patent
LigandPNGBDBM483000(US10919885, Compound No. 148)
Affinity DataIC50: 4.00E+3nMAssay Description:Strains expressing SCD1 or SCD5 as the sole desaturase, the human SCD1 and SCD5 genes were used to evaluate inhibition of SCD1/SCD5 using reduced gro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetStearoyl-CoA desaturase 5(Human)
Yumanity Therapeutics

US Patent
LigandPNGBDBM483000(US10919885, Compound No. 148)
Affinity DataIC50: 350nMAssay Description:Strains expressing SCD1 or SCD5 as the sole desaturase, the human SCD1 and SCD5 genes were used to evaluate inhibition of SCD1/SCD5 using reduced gro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent