BDBM48290 MLS000566310::N-(1H-benzimidazol-2-yl)benzamide::SMR000153404::cid_2302856

SMILES O=C(Nc1nc2ccccc2[nH]1)c1ccccc1

InChI Key InChIKey=LYLQJTSHZYGWBO-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 48290   

TargetMatrix metalloproteinase-14 [1-36](Human)
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM48290(cid_2302856 | SMR000153404 | MLS000566310 | N-(1H-...)
Affinity DataEC50:  3.53E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetMetabotropic glutamate receptor 5(Mouse)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM48290(cid_2302856 | SMR000153404 | MLS000566310 | N-(1H-...)
Affinity DataIC50: 1.60E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM48290(cid_2302856 | SMR000153404 | MLS000566310 | N-(1H-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using tyramine as substrate preincubated for 30 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM48290(cid_2302856 | SMR000153404 | MLS000566310 | N-(1H-...)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [3H]ZM241385 from A2A receptor in human HeLa cell membranes after 30 mins by beta-scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details Article
PubMed