BDBM482872 US10919885, Compound No. 20

SMILES FC(F)(F)c1cccc(Cn2cc(NC(=O)c3cc(on3)-c3ccco3)cn2)c1

InChI Key InChIKey=STDKBUREMSMCQL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482872   

TargetStearoyl-CoA desaturase(Human)
Yumanity Therapeutics

US Patent
LigandPNGBDBM482872(US10919885, Compound No. 20)
Affinity DataIC50: 4.50E+4nMAssay Description:Strains expressing SCD1 or SCD5 as the sole desaturase, the human SCD1 and SCD5 genes were used to evaluate inhibition of SCD1/SCD5 using reduced gro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetStearoyl-CoA desaturase 5(Human)
Yumanity Therapeutics

US Patent
LigandPNGBDBM482872(US10919885, Compound No. 20)
Affinity DataIC50: 200nMAssay Description:Strains expressing SCD1 or SCD5 as the sole desaturase, the human SCD1 and SCD5 genes were used to evaluate inhibition of SCD1/SCD5 using reduced gro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent