BDBM482856 US10919885, Compound No. 4

SMILES O=C(Nc1cnn(Cc2ccccc2)c1)c1cc(on1)-c1ccco1

InChI Key InChIKey=TXRXZXXDVZMXQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482856   

TargetStearoyl-CoA desaturase(Human)
Yumanity Therapeutics

US Patent
LigandPNGBDBM482856(US10919885, Compound No. 4)
Affinity DataIC50: 90nMAssay Description:Strains expressing SCD1 or SCD5 as the sole desaturase, the human SCD1 and SCD5 genes were used to evaluate inhibition of SCD1/SCD5 using reduced gro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetStearoyl-CoA desaturase 5(Human)
Yumanity Therapeutics

US Patent
LigandPNGBDBM482856(US10919885, Compound No. 4)
Affinity DataIC50: 70nMAssay Description:Strains expressing SCD1 or SCD5 as the sole desaturase, the human SCD1 and SCD5 genes were used to evaluate inhibition of SCD1/SCD5 using reduced gro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent