BDBM482742 (1S,2S)-2-{5-[(4,6,3′,5′-Tetrafluoro-4′-methoxy-biphenyl-3-ylmethyl)-amino]-pyridin-2-yl}-cyclopropanecarboxylic acid::US10919859, Example 10

SMILES COc1c(F)cc(cc1F)-c1cc(CNc2ccc(nc2)[C@H]2C[C@@H]2C(O)=O)c(F)cc1F

InChI Key InChIKey=GPZNMZOICRIPHN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 482742   

TargetFree fatty acid receptor 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM482742(US10919859, Example 10 | (1S,2S)-2-{5-[(4,6,3̸...)
Affinity DataEC50:  52nMAssay Description:IP1 accumulation measurements using the IPOne assay system 1321N1 cells stably expressing human GPR40 receptor (Euroscreen, Belgium) are seeded 24 h ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
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