BDBM482737 (1S,2S)-2-(5-{([4′-(3-Hydroxy-3-methyl-butoxy)-2′,6′-dimethyl-6-trifluoromethyl-biphenyl-3-ylmethyl]-amino}-pyridin-2-yl)-cyclopropanecarboxylic acid::US10919859, Example 5

SMILES Cc1cc(OCCC(C)(C)O)cc(C)c1-c1cc(CNc2ccc(nc2)[C@H]2C[C@@H]2C(O)=O)ccc1C(F)(F)F

InChI Key InChIKey=GYGBHWHEDYMSJB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 482737   

TargetFree fatty acid receptor 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM482737(US10919859, Example 5 | (1S,2S)-2-(5-{([4′-(...)
Affinity DataEC50:  12nMAssay Description:IP1 accumulation measurements using the IPOne assay system 1321N1 cells stably expressing human GPR40 receptor (Euroscreen, Belgium) are seeded 24 h ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
US Patent