BDBM482736 (1S,2S)-2-{5-[(4′-Trifluoromethoxy-6-trifluoromethyl-biphenyl-3-ylmethyl)-amino]-pyridin-2-yl}-cyclopropanecarboxylic acid::US10919859, Example 4

SMILES OC(=O)[C@H]1C[C@@H]1c1ccc(NCc2ccc(c(c2)-c2ccc(OC(F)(F)F)cc2)C(F)(F)F)cn1

InChI Key InChIKey=PAOIEVACOOZGKP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 482736   

TargetFree fatty acid receptor 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM482736(US10919859, Example 4 | (1S,2S)-2-{5-[(4′-Tr...)
Affinity DataEC50:  44nMAssay Description:IP1 accumulation measurements using the IPOne assay system 1321N1 cells stably expressing human GPR40 receptor (Euroscreen, Belgium) are seeded 24 h ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
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