BDBM482322 US10919852, Compound TABLE 1.21::US10919852, Compound TABLE 1.24::US11708326, Compound TABLE 1.21

SMILES C[C@@](CO)(NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2cccc(OCCCN3CCC(O)CC3)c2Cl)cc1OCc1cncc(c1)C#N)C(O)=O

InChI Key InChIKey=VZGCZMANPBKHGC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 482322   

TargetProgrammed cell death protein 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM482322(US10919852, Compound TABLE 1.21 | US10919852, Comp...)
Affinity DataIC50: 5nMAssay Description:96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetProgrammed cell death protein 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM482322(US10919852, Compound TABLE 1.21 | US10919852, Comp...)
Affinity DataIC50: 5nMAssay Description:96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM482322(US10919852, Compound TABLE 1.21 | US10919852, Comp...)
Affinity DataIC50: 5nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent