BDBM482315 US10919852, Compound TABLE 1.14::US10919852, Compound TABLE 1.15::US11708326, Compound TABLE 1.15

SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cc(cc(c2)C#N)C#N)c(CN[C@@](C)(CO)C(O)=O)cc1Cl

InChI Key InChIKey=BVMKIPFXRSKXJJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 482315   

TargetProgrammed cell death protein 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM482315(US10919852, Compound TABLE 1.14 | US10919852, Comp...)
Affinity DataIC50: 5nMAssay Description:96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetProgrammed cell death protein 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM482315(US10919852, Compound TABLE 1.14 | US10919852, Comp...)
Affinity DataIC50: 5nMAssay Description:96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM482315(US10919852, Compound TABLE 1.14 | US10919852, Comp...)
Affinity DataIC50: 5nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM482315(US10919852, Compound TABLE 1.14 | US10919852, Comp...)
Affinity DataIC50: 5nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
Go to US Patent