BDBM482246 4-cyclopentyl-5,11-dihydro- 4H-3,4,10,11-tetraazadibenzo [cd,h]azulene::US10918645, Example 38::US10918645, Example 52

SMILES O=c1n(C2CCCC2)c2nccc3[nH]nc(c23)c2ccccc12

InChI Key InChIKey=BRGCSGJDTDEUEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482246   

LigandPNGBDBM482246(US10918645, Example 52 | 4-cyclopentyl-5,11-dihydr...)
Affinity DataIC50: 33nMAssay Description:TTBK1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 1 mg/ml BSA, 10 mM DTT) is assayed against RRKDLHDDEEDEAMSITA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

LigandPNGBDBM482246(US10918645, Example 52 | 4-cyclopentyl-5,11-dihydr...)
Affinity DataIC50: 180nMAssay Description:TTBK1 (5-20 mU diluted in 50 mM Tris pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 1 mg/ml BSA, 10 mM DTT) is assayed against RRKDLHDDEEDEAMSITA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent