BDBM481949 US10913753, Compound I-16

SMILES Nc1c(sc2nc(N)cc(C(F)F)c12)C(=O)NCCc1ccc(cc1)N1CCNCC1

InChI Key InChIKey=SRTMEUZKKHKITG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 481949   

TargetUbiquitin carboxyl-terminal hydrolase 28(Human)
Valo Early Discovery

US Patent
LigandPNGBDBM481949(US10913753, Compound I-16)
Affinity DataIC50: 200nMAssay Description:USP28: The assay was performed in a final volume of 20 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandPNGBDBM481949(US10913753, Compound I-16)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
Go to US Patent