BDBM481913 (3aR,6aS)-3,5-Dichlorobenzyl 5-(4-acetamidobenzoyl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate::US10913745, Example 2::US10913745, Example 2.01

SMILES CC(=O)Nc1ccc(cc1)C(=O)N1C[C@@H]2CN(C[C@@H]2C1)C(=O)OCc1cc(Cl)cc(Cl)c1

InChI Key InChIKey=DLTXTAJZWQZYIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 481913   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481913(US10913745, Example 2 | US10913745, Example 2.01 |...)
Affinity DataIC50: 342nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481913(US10913745, Example 2 | US10913745, Example 2.01 |...)
Affinity DataIC50: 1.50E+3nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent