BDBM48184 2-(3-chlorophenyl)-5-phenyl-1,3,4-oxadiazole::2-phenyl-5-(3-chlorophenyl)-1,3,4-oxadiazole (2d)::MLS000108072::SMR000104035::cid_259755

SMILES Clc1cccc(c1)-c1nnc(o1)-c1ccccc1

InChI Key InChIKey=HFKZYMPEMMAFOG-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 48184   

TargetMatrix metalloproteinase-14 [1-36](Human)
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM48184(cid_259755 | MLS000108072 | SMR000104035 | 2-(3-ch...)
Affinity DataEC50:  7.03E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetTranscription factor p65(Human)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM48184(cid_259755 | MLS000108072 | SMR000104035 | 2-(3-ch...)
Affinity DataEC50:  1.67E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetOxysterols receptor LXR-beta(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM48184(cid_259755 | MLS000108072 | SMR000104035 | 2-(3-ch...)
Affinity DataEC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetCathepsin L(Goat)
Kurukshetra University

LigandPNGBDBM48184(cid_259755 | MLS000108072 | SMR000104035 | 2-(3-ch...)
Affinity DataKi:  70.2nM ΔG°:  -10.1kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2016
Entry Details Article
PubMed
TargetCathepsin H(Goat)
Kurukshetra University

LigandPNGBDBM48184(cid_259755 | MLS000108072 | SMR000104035 | 2-(3-ch...)
Affinity DataKi:  1.13E+3nM ΔG°:  -8.43kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2016
Entry Details Article
PubMed
TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM48184(cid_259755 | MLS000108072 | SMR000104035 | 2-(3-ch...)
Affinity DataKi:  1.28E+3nM ΔG°:  -8.36kcal/molepH: 5.0 T: 2°CAssay Description:The proteolytic activity was estimated at pH 5.0, 37 °C using 0.1 M acetate buffer as the incubation medium. The homogenate prepared above was incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2016
Entry Details Article
PubMed