BDBM481748 US10913711, Compound 12a::US11555013, Compound 12a

SMILES O=C(CS(=O)C(c1ccccc1)c1ccccc1)N1CCN(CCCc2ccccc2)CC1

InChI Key InChIKey=XKMVRRAMCQYRRJ-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 481748   

TargetSodium-dependent dopamine transporter(Rat)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM481748(US10913711, Compound 12a | US11555013, Compound 12...)
Affinity DataKi:  33nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM481748(US10913711, Compound 12a | US11555013, Compound 12...)
Affinity DataKi:  33nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
US Patent

TargetSigma intracellular receptor 2(Rat)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM481748(US10913711, Compound 12a | US11555013, Compound 12...)
Affinity DataKi:  469nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Rat)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM481748(US10913711, Compound 12a | US11555013, Compound 12...)
Affinity DataKi:  1.43E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Rat)
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM481748(US10913711, Compound 12a | US11555013, Compound 12...)
Affinity DataKi:  1.52E+4nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Rat)
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM481748(US10913711, Compound 12a | US11555013, Compound 12...)
Affinity DataKi:  1.52E+4nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetNeuroepithelial cell-transforming 1(Rat)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM481748(US10913711, Compound 12a | US11555013, Compound 12...)
Affinity DataKi:  5.43E+4nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetTransporter(Rat)
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM481748(US10913711, Compound 12a | US11555013, Compound 12...)
Affinity DataKi:  5.43E+4nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
US Patent