BDBM481746 N-[1-(1H-indol-3- ylmethyl)pentyl]-2-[4-(4- pyridyl)piperazin-1- yl]thiazole-5-carboxamide::US10913735, Example 3

SMILES CCCCC(Cc1c[nH]c2ccccc12)NC(=O)c1cnc(s1)N1CCN(CC1)c1ccncc1

InChI Key InChIKey=IFNAMTFNURMFRP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481746   

TargetAlpha-synuclein(Human)
Ucb Biopharma

US Patent
LigandPNGBDBM481746(N-[1-(1H-indol-3- ylmethyl)pentyl]-2-[4-(4- pyridy...)
Affinity DataIC50: 2.70E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent