BDBM481744 N-[1-(1H-indol-3- ylmethyl)pentyl]-2-(4- pyrimidin-5-ylpiperazin-1- yl)thiazole-5-carboxamide::US10913735, Example 1

SMILES CCCCC(Cc1c[nH]c2ccccc12)NC(=O)c1cnc(s1)N1CCN(CC1)c1cncnc1

InChI Key InChIKey=KGRRDPOBYBLURM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481744   

TargetAlpha-synuclein(Human)
Ucb Biopharma

US Patent
LigandPNGBDBM481744(N-[1-(1H-indol-3- ylmethyl)pentyl]-2-(4- pyrimidin...)
Affinity DataIC50: 1.40E+3nMAssay Description:The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent