BDBM481632 N1-(4-chlorobenzyl)-N1-cyclopentyl- N4-(piperidin-4-ylmethyl)benzene- 1,4-disulfonamide::US10913710, Compound 45

SMILES Clc1ccc(CN(C2CCCC2)S(=O)(=O)c2ccc(cc2)S(=O)(=O)NCC2CCNCC2)cc1

InChI Key InChIKey=OLBHRXYBEVLWOQ-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481632   

TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Human)
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US Patent
LigandPNGBDBM481632(N1-(4-chlorobenzyl)-N1-cyclopentyl- N4-(piperidin-...)
Affinity DataKd:  16nMAssay Description:Binding to PDEδ was validated and quantified by means of a displacement assay employing a fluorescent-tagged analog of the HMG-CoA reductase inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent