BDBM481207 6-((5S,8R)-2-(Pyridin-2-yl)-5,6,7,8-tetrahydro-5,8-methanoimidazo[1,2-a]pyridin-3-yl) quinoline-4-carboxamide 45-1::US10906905, Example 45-1

SMILES NC(=O)c1ccnc2ccc(cc12)-c1c(nc2[C@@H]3CC[C@@H](C3)n12)-c1ccccn1

InChI Key InChIKey=WJYMSSHTDGFYAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481207   

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM481207(6-((5S,8R)-2-(Pyridin-2-yl)-5,6,7,8-tetrahydro-5,8...)
Affinity DataIC50: 29nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
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Date in BDB:
8/22/2021
Entry Details
US Patent