BDBM481165 US10906905, Example 4-2

SMILES Cc1cccc(n1)-c1nc2[C@H]3CC[C@H](C3)n2c1-c1ccnc(c1)-c1ccc(cc1)C(N)=O

InChI Key InChIKey=DOBRZXIRNFXQCN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481165   

TargetTGF-beta receptor type-1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM481165(US10906905, Example 4-2)
Affinity DataIC50: 18nMAssay Description:TGFβRI kinase assay kit (V4093, Promega) was used to assay enzyme activity. 2 μl of enzyme solution (the final concentration of enzyme in t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent