BDBM480917 7-oxa-2-azaspiro[3.5]non-2-yl(2-{[2-(pyrazin-2-yl)propan-2-yl]amino}pyrimidin-5-yl)methanone::US10906888, Example 131
SMILES CC(C)(Nc1ncc(cn1)C(=O)N1CC2(C1)CCOCC2)c1cnccn1
InChI Key InChIKey=ZAZCXKUHBDUQPR-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 480917
Affinity DataIC50: 0.0940nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:Inhibition of mouse vanin-1More data for this Ligand-Target Pair
Affinity DataIC50: 0.880nMAssay Description:Inhibition of human plasma vanin-1 using pantetheine-7-amino-4-trifluoromethykournarin as substrate preincubated for 30 mins followed by substrate ad...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair