BDBM480684 N-[6-morpholino-1-oxo-2-[rac- (2R)-2-fluoro-3-hydroxy-3- methyl-butyl]isoindolin-5-yl]- [1,2,4]triazolo[1,5-a]pyridine- 5-carboxamide::US10899772, Example 34

SMILES CC(C)(O)[C@H](F)CN1Cc2cc(NC(=O)c3cccc4ncnn34)c(cc2C1=O)N1CCOCC1

InChI Key InChIKey=JAXFMBJLSZEQBY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480684   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM480684(US10899772, Example 34 | N-[6-morpholino-1-oxo-2-[...)
Affinity DataKi:  2.80nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2021
Entry Details
Go to US Patent